Report of Forty-eight Cases of Marginal Blepharitis Treated with Penicillin.

MARGINAL, blepharitis is a relatively 'common and partic.ularly intractable inflammation of the lid margins, -usually attributed to~ infection' with staphylococcus awreus. I-n the past a vdy4ety of, treatm-ents have, been -tried,, includ-ing the application to the lid margins' of ointments (e.g., hyd. ox. flav., ung. y ,am. dil., un.g. zinc et ichthyol.', ung. sulph-onamidIe, etc.), of d-ye solutions (e.. liq. tinct., miercurochrome), of naild antisep'tics (protargol, argyr,ol), and, of caustics :(1 per cent. silver niitrate and 065 per cent,. di'lute carbolic). Combined with\ these treat..!, ments epilation of 'the lashes, 'autogenous and stock staphylococcus aureus vaccines, staphylococcal toxoid,. correction of errors of refr'action, 'vitamins, and remov-al 'of septic foci "have. 'also -been recommended. Treatment of the usually associated seborrhoe'a capitis is also considered essential by many observers. The multiplicity of treatments alone indicates the intractable nature of the disease. It tends to' improve uncfer all or any of them.for a time, but usually shows frequent reklapses and, may pass, easily into a chronic stage which may be life long. The following investigation was carried out in order to test the